The importance of intracytoplasmic DPAS positivity in fine needle aspirates of breast lesions
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چکیده
منابع مشابه
The importance of intracytoplasmic DPAS positivity in fine needle aspirates of breast lesions.
AIMS For many years the presence of strong intracytoplasmic periodic acid Schiff (PAS) positive, diastase resistant (DPAS) staining within atypical cells has been used in this laboratory as a marker for carcinoma in fine needle aspirates from breast lesions. The aim of the current study was to document such DPAS positivity across the spectrum from benign to malignant breast disease and assess i...
متن کاملAtypia in fine needle aspirates of breast lesions.
BACKGROUND The atypical category is controversial in fine needle aspiration cytology (FNAC) of the breast; most are benign, but a significant number are malignant. To date, no morphological criterion has been found to be consistent in predicting malignancy. AIMS To evaluate specific cytological parameters and assess their usefulness in predicting histological outcome in a cohort of atypical b...
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Thirty six fine needle aspirates from various types of benign breast lesions were examined by electron microscopy and correlated with their cytological appearances. In all cases the parenchyma consisted of clumps of cohesive cells with the ultrastructural features of epithelial cells. In many cases, particularly from fibroadenomas, the parenchyma consisted of single layers of polarised epitheli...
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The goal of this work is to determine the accuracy of computer-based image analysis in diagnosing breast fine-needle aspirates (FNA). On 192 FNAs, the computerbased diagnostic accuracy was 97.9%. This is consistent with the 97.5% accuracy projected by machine learning methods during the initial training in 1994 with 569 FNAs. One of the attributes of this system is the rendering of a value that...
متن کاملIn search of specimen adequacy in fine-needle aspirates of nonpalpable breast lesions.
Pathology-related medical malpractice claims frequently concern fine-needle aspirations (FNAs) of breast lesions, and diagnostic errors have been attributed in part to the inadequacy of the specimens. Cytologic criteria for adequate FNA specimens, specifically in cases without malignancy, have not been clearly defined. From January 1988, to August 1995, 669 ultrasonographic-guided FNAs of nonpa...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 2001
ISSN: 0021-9746
DOI: 10.1136/jcp.54.2.146